The Houston Astros have won only 2 Wild Cards. These Wild Cards were won in 2005 and 2006.

The 2004 Houston Astros Season

The 2004 Houston Astros season was their 43rd in Major League Baseball (MLB). The Astros hosted the All-Star Game for the first time since 1986, five years after opening Minute Maid Park. Phil Garner, who had a 44–44 record into the All-Star break, replaced Jimy Williams as manager.

Their second-place result in the Central gave them the NL Wild Card. The Astros won their first playoff series ever by beating the Atlanta Braves in the NLDS with an NLDS record of 36 runs. It was Clemens’ fourth Cy Young Award in both leagues, and his seventh overall.

The 2005 Houston Astros Season

The 2005 Houston Astros season was their 44th in Major League Baseball (MLB). They made the playoffs for the second straight year and the sixth time in nine seasons. The Astros had been one win away from a pennant the previous year. But they started at 15–30. They would go on to win the National League pennant and advance to the World Series for the first time in team history, hosting the first World Series game in Texas.

But the Chicago White Sox swept them in the World Series. It was Jeff Bagwell’s final season and first World Series participation.

But it was also the last postseason participation for 10 years, as stars like Bagwell retired.